Gentamicin sulfate-UHMWPE spacer implant for two-stage revision surgery / Source: Orhun Muratoglu, Ph.D.

A team from the Harris Orthopedics Laboratory at Massachusetts General Hospital and the Department of Orthopaedic Surgery at Harvard Medical School has developed and tested a novel antibiotic loaded UHMWPE material that combines structural function with localized drug delivery.

The results of that study, “Enhanced Antibiotic Release and Mechanical Strength in UHMWPE Antibiotic Blends: The Role of Submicron Gentamicin Sulfate Particles,” appears in the March 19, 2025 edition of The Journal of Bone and Joint Surgery.


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