Illustration of unilateral knee swelling consistent with arthritis or knee effusion / Source: Wikimedia Commons and Centers for Disease Control and Prevention

Every knee surgeon knows the drill: you line up your pre-op images, measure your angles, and prep for total knee arthroplasty (TKA). But let’s be honest — sometimes that arthritic knee you’re about to cut into feels like it didn’t read the textbook.

Now, a new study suggests that’s because knees don’t all follow the same playbook. In fact, they fall into four distinct 3D phenotypes.


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