A new meta-analysis from Brown University has found evidence that vancomycin may not prevent surgical site infections (SSIs) after spine surgery as effectively as some surgeons expect. The Brown University meta-analysis appears in the December 1, 2024 edition of Clinical Orthopaedics and Related Research: under the title: “Does the Application of Topical Vancomycin Reduce Surgical Site Infections in Spine Surgery? A Meta-analysis of Randomized Controlled Trials.”
This study collected data from and analyzed six randomized controlled trials with 2,140 patients (1,053 in the vancomycin group and 1087 in the control group).
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