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New work performed at the OrthoCarolina Research Institute in Charlotte, North Carolina, the nonprofit research partner of OrthoCarolina, highlights a truly novel, scalable, opioid-free recovery protocol known as the CORE (Carolinas Opioid Reduction Effort) program.

The study, “An Opioid-Free Perioperative Pain Protocol Is Noninferior to Opioid-Containing Management: A Randomized Controlled Trial,” appears in the April 2, 2025, edition of The Journal of Bone and Joint Surgery.


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