Centinel Spine’s prodisc Total Disc Replacement set new records in 2024, according to the company, and this accelerated growth is expected to continue in 2025.
Centinel Spine, LLC is a West-Chester, Pennsylvania-based global medical device company exclusively focused on treating cervical and lumbar spinal disease with its total disc replacement technology platform.
Centinel Spine CEO Steve Murray said in a statement, “The Centinel Spine team achieved records in all aspects of our global business in 2024. We are exclusively committed to total disc replacement, with the goal of becoming the clear global leader in this fast-growing segment of the spine market.”
prodisc Total Disc Replacement revenue for the full-year 2024 was over $95 million, up 38% over 2023.
Both international and U.S. sales grew substantially during the year. In the U.S., sales increased 41% while international sales experienced a 24% year-over-year increase.
prodisc Cervical revenue for the year was over $59 million, which was a 39% year-over-year increase. prodisc Lumbar revenue was almost $36 million, a 35% improvement to 2023.
The company also reported that over 1,000 U.S. healthcare facilities used prodisc in 2024, up 28% from the previous year.
Fourth Quarter Highlights
For the fourth quarter alone, prodisc Total Disc Replacement revenue was up 47% from the year before with a revenue of almost $30 million.
- Global prodisc Cervical revenue of almost $17 million, a 38% year-over-year increase.
- Global prodisc Lumbar revenue of almost $13 million, a 62% year-over-year increase.
- S. prodisc Total Disc Replacement revenue of more than $25 million, up 52% from the previous year.
- International prodisc Total Disc Replacement revenue of $4.6 million, up 27% from the previous year.
Match-the-Disc prodisc Cervical TDR System
Since its limited release in Third Quarter 2022, the Match-The-Disc prodisc Cervical TDR System has steadily increased its sales growth. By the end of 2024, more than 9,000 procedures had been completed in the U.S. using the new system, making it a major driver in the record growth in U.S. prodisc Cervical sales.
More than 900 surgeons are now using the system. In 2024, new surgeons were added at an average of more than 100 a quarter, according to the company.
The prodisc C Vivo implant features a domed, keel-less endplate that make one-step implantation easier. It also has unique spikes that provide equivalent fixation to keeled devices.
The prodisc C SK features the flat endplates and keel fixation of prodisc C, but it has a smaller keel, and the preparation of the keel is simplified.
The prodisc C Nova has unique tri-keels designed to improve fixation in certain endplate morphologies.
All three of these implants were designed with an anatomical trapezoidal footprint shape that lessens intraoperative remodeling.
The original prodisc C implants utilize flat endplates with larger central keels. What makes prodisc CORE technology unique is its fixed center of rotation which was designed to stabilize the motion segment and resist shear forces.
A Recipe for Continued Growth in 2025
Murray said all of this has positioned the company for accelerated growth in 2025. One of the key ingredients for another record year is that with the recent release of the prodisc C Nova technology,
Centinel Spine now offers four anatomic products in the Match-the-Disc prodisc Cervical TDR System.
prodisc Lumbar revenue is also continuing to grow. Surgeons can now choose anatomic endplates that provide a more customized fit to the patient through full range of levels L3 to S1. Reimbursement for lumbar total disc replacement has also been expanding increasing access to patients, and now there is more positive long-term implant survivorship data available to validate the prodisc L Lumbar total disc replacement system.
Other important ingredients the company said are:
- Centinel Spine added 665 new prodisc users in the U.S. in 2024, which was a 90% increase from the previous year.
- As more patients become aware of the potential benefits of these motion-preserving systems, the demand for them is expected to increase.
- Through the company’s global Medical Education program, over 800 surgeons were trained in 2024.
- Th prodisc implant manufacturing capacity expanded throughout 2024 strengthening the supply chain.
Murray added, “The prodisc technology not only offers the benefits of our ‘Match-the-Disc’ innovation, it is coupled with the longest demonstrated history of clinical success in disc replacement. We are all-in on total disc replacement and well-positioned for continued success in 2025 and beyond.”

